Advice

Key learnings and advice from our journeys...

Any advice you want to add? Reach out!

Post-PhD Paths

You have a science background and are interested in 'the business side of science'. 

What options do you have?

Here are the main options I was considering when making the transition from the PhD into the business side of science, what I knew then, and what I have learned since. The commentary is of course all from my perspective, so please consider that your pros and cons may differ!


Industry scientist position: stay at the bench, but move into industry with the goal of working your way over to the business side.

Pro: most immediately relevant role, given your background. You will start being exposed tangentially to corporate processes depending on the size of the company

Con: it can be difficult to successfully move from a scientist role to a business role internally and is not a common path. That being said, if you are willing to wait until later in your career, these roles eventually have some business considerations included in the work!


The more school options: leverage additional educational opportunities or training to build the skill set necessary to land a job away from the bench. 

Pro: clearest training in business skills and acumen. These programs typically prioritize expanding your network, internships, and job placement

Con: more school and investment

Pro: for those who brave it, the combination of a PhD and law degree can be extremely attractive for roles such as intellectual property (IP) lawyer or in venture capital 

Con: so much more school and investment

Con: while it may be necessary to buy time, those reviewing your resume from the business side often do not value the post doc. The question becomes, "If you wanted to go into the business side, why did you waste time doing more science?" The only caveat would be if you are working on starting a company during this time, which can be a very helpful experience in looking for your next non-science role


Find a job that will train you: take an entry-level position at an organization that will give you your first business experience.

Pro: broadest range of experience and skills learned in the shortest amount of time all with decent pay

Con: no work-life balance with the high stress and pace of the consulting firms trying to fit in as many projects as possible with as few people as they can manage to maximize profits

Pro: commonly hire associates who have a science background, but very little or no experience (although some demonstrated interest) in the business side. Can involve staying close to exciting new science, passionate entrepreneurs, and successful company creators. The pay is typically pretty good

Con: it varies, but I have seen that the schedule can be busy for some VC firms. For me, everything being very early stage did not satisfy my desire to bring solutions to patients in the near term. The business acumen and training you get can be very practical (e.g., how to get a company up and running, identify what ideas have market potential, and investment strategy), but doesn't typically give you insight into how larger companies operate

Pro: starts to get you thinking about what it takes to translate science into solutions for customers, how intellectual property is valued, and basic contracting

Con: this is more something you can do while you are still in school to get experience on your resume. If you do want to go into Tech Transfer as a career, you may need additional training or experience before you would be eligible for the role. The business skills you learn here are also not as complete as the training you would get in some of the other roles

Pro: if you enjoy communicating clinically relevant data to physicians, then this can be a great way to dip your toe into the world of industry away from the bench while still heavily leveraging your scientific acumen 

Con: these roles do not give you direct training in common business skills such as forecasting, building business cases, market research, strategy, etc. Though it is easier to transition into those more classic business roles than it would be from a pure scientist role


Which one would you go for?

Michaela Tolman, PhD

Informational Interviews

Crucial step! Over 50% of roles are filled through personal connections.

What is an informational interview?

Think of yourself as a reporter. Your goal in an informational interview is just to learn through a conversation.

If you don't reach out, you will be behind on your goals and make less-informed decisions. 

If you do reach out, here are some potential benefits:

The worst thing that could happen is that the person does not reply or says no - both of which are fine!

See the 'Resources' page for a networking tracking template


Be sure to...


Inspiration for how to approach the conversation:

About you (concise) 

About them (most of the time)

Next steps


Michaela Tolman, PhD

Company Size

What are the pros and cons of small, medium, and large companies? Which is right for me now?


Small (<100 employees)

Pros

Cons


Medium (100-1,000 employees)

Pros

Cons


Large (1,000+ employees)

Pros

Cons

Michaela Tolman, PhD

Company Structure

What are the typical departments within a company? 

This varies greatly by the size of the company and stage of their products! Outlined below are the departments you would find in a larger commercial-stage company. Even then, these functions can be found in various different combinations. The smaller or earlier stage the company is, not all of these are needed and the more roles span a few of these functions. 

In no particular order:

Corporate strategy - the team working on cross-functional strategic problems, processes, and setting the long-term goals for the company

Business development (BD) - the group responsible for handling licensing deals, company mergers and acquisitions

External Innovation (EI) - sometimes a part of business development, but if separate, this group focuses on scouring the world for any interesting new science to leverage

Legal - apart from handling any lawsuits, the legal team plays a key role in mitigating risk for the company. It can also include a separate intellectual property (IP) team focused on patents and topics around marketing exclusivity 

Finance - the finance team is pretty self-explanatory. They manage all of the money coming in, going out, and associated taxes and reporting requirements

Research and Development (R&D) - this is where the scientists live. Anything still in the screening, validation, or exploration phases would be here

Clinical Development - once a product is being tested in humans (in the clinic) through the clinical trial process, the clinical development team comes in to write the trial protocols and engage with hospitals and regulators

Medical - the medical team is responsible for educating and engaging the healthcare community. At the global level, they can help plan what data we need to generate to support the product and advocate for inclusion in medical guidelines. At the local level, medical sales liaisons (MSLs) engage directly with potential customers

Regulatory - simply having a product and completing clinical trials is not enough. You also need to engage with the regulatory agencies (e.g., FDA, EMA, etc.) that approve new products or therapies. This group leads those interactions 

Value and Acces (V&A) - sometimes also called market access, this team is crucial for setting the price of the product and engaging with payers (insurance companies) to ensure that the product is readily available and affordable to your future customers. This function also may have a global team and separate local teams responsible for each country or region

Pharmaceutical Operations and Technology (PO&T) - there are no clinical trials or sales without the product itself. The operations team is crucial for ensuring the production and distribution of the product

Commercial - this is the team that markets and sells the product. Depending on the size of the company, there can be a global function and separate regional or local commercial teams that ultimately ladder down to the sales representatives contacting customers

Forecasting - this team is responsible for plugging in all of the key program or company assumptions into excel and projecting the associated financial implications or calculating the financial impact of different scenarios

Insights - to make sound strategic decisions, you need to understand your customers and the marketplace. The insights team typically works with agencies to perform market research, track trends, monitor competitors, and synthesize implications for the company

Portfolio Management - with multiple products, it becomes important to prioritize across your investments. The portfolio management team works to align spending and effort with the company's overall strategy

Program Management - with all of the functions mentioned so far...hopefully it is clear that someone needs to keep us all on track. Program managers set schedules, timelines, faciliate, and generally manage everything going on in cross-functional teams

Product Team - this is called a number of things (product development team, lifecycle team, etc.) and is basically a small company within the company focused on advancing a single product. Most members report into their various functions, but spend the majority of their time working with others to advance their product of focus

Chief of Staff - many corporate leaders have a 'right hand' person who can help triage information and stand in for him/her in various forums

Human Resources - also known as the 'People Team', HR works to monitor and improve the company culture, resources for development, optimizing compensation among other things

Michaela Tolman, PhD

Corporate Leveling

What are the different levels for each role? Where would should I be, given my experience?

This is a tricky one. I have outlined the most common levels I have seen below, but it should be noted that titles differ widely between and even within companies. The amount of experience needed for a manager role at a start up is not the same as the amount of experience needed at a large company (the bar is often higher at larger organizations) or even the same from one team to another within the same company. 

From least to most experience required:

Michaela Tolman, PhD

Business Processes

Well-established companies work on annual cycles. These cycles are punctuated by universal planning processes. Becoming familiar with these now will help you get up to speed quickly in your first industry position, better partner with client companies, or elevate the level of planning in your current organization. 

Common corporate processes typically focus on either financials or strategy:

Financial Processes

Long range planning focuses on the 3-5 years from now timeframe (though many companies like to keep an even longer high-level view out to 10 or 15 years). Each product and function need to estimate how much money it will bring in (revenue) and how much money it will need (costs). Summing all the revenues and costs across the company allows for a corporate outlook and helps inform prioritization and strategy decisions. LRPs are typically re-calibrated or set in the first half of the year.

Annual operating plans focus on the next 1 year timeframe. They include a detailed view of the costs required to accomplish each function's tasks in the following year. These are typically submitted in the second half of the year and approved late that same year or early the following year to allow for unlocking of funds and kicking off of workstreams and hiring in the new year.

For public companies, financial reports are owed to shareholders and the public at the close of each quarter of the year (Q1 in April, Q2 in July, Q3 in October, and Q4 in January). These are typically standard readouts led by the finance team where the company announces how much cash, debt, costs, and income they have had in the previous three months. 

Strategic Processes

Depending on the product or business unit's stage, each year they are typically asked to create or refresh their plan or strategy. This process can be called brand planning, integrated customer planning, or some variation thereof and usually happens in the first part of the year prior to the broader disease or therapeutic area planning. 

The general steps are as follows:

If you focus solely on the plan for each product in isolation, you may miss synergies or opportunities to maximize your potential in the disease or therapeutic area as a whole. For example, you are selling apples in the fall and your apple strategy is to buy all the crates, stands, signs etc. and to then throw them out at the end of the season, because it is cheaper to do so than to pay for storage. You are also selling oranges in the winter. Your orange strategy also requires buying crates, stands, signs, etc. and throwing them away at the end of the season. If you look across your whole fruit strategy, you can see that there are cost savings by using the same crates, stands, signs etc for your apple season and your orange season. It may require some re-painting, but on the whole, you are maximizing your resources. 

Michaela Tolman, PhD

Slide Creation

Slide creation is an art more than a science, but there are a few key tips that will help you elevate your game. 

Content

Formatting

Tools

Until these become automatic, I used to keep many of these as a checklist or sticky notes on my computer to reference before sending a presentation

Michaela Tolman, PhD

Prioritization

In very few settings can you do everything. Even if you can do everything, you probably don't need to/shouldn't and will be asked to prioritize or rank the importance of each opportunity/thing you want to do.

There are many ways to prioritize your efforts. For making any trade-off decision, you should weigh the pros and cons - also known as a cost/benefit analysis or 'business case'. Here are a few common metrics for consideration:

Cost

Benefit

In general, you want to maximize what you get out (benefit) for what you put in (cost).  To summarize all of these considerations, it can be helpful to create a heat map in table format, a 2x2 graph plotting different options along the axes of cost and benefit, and/or put financial numbers to the different options with an NPV (net present value) assessment. 

Michaela Tolman, PhD

Teambuilding 

How can I increase awareness of my own working style and help my team work better together?

(See examples on the 'Resource' page)


Michaela Tolman, PhD

Consulting Firms

What consulting firms are out there?

So many!

Here are two types of consulting firms generally open to those of us coming from a science background:

The 'Big 3' and Generalist Consulting Firms: These are firms that work on generally a wide range of project types and across many different types of industries. 

Pros

Cons

Examples


Boutique Life Sciences Consulting Firms: smaller firms focused on biotech and healthcare exclusively. They may be part of a larger organization or stand alone and there are many!

Pros

Con

Examples

Michaela Tolman, PhD

Consulting Firm Application Cycles

When is the best time to apply to consulting firms? 


These days, consulting firms are almost always looking for new talent. That being said, there are typical recruiting cycles that you should be aware of. 


If you are coming from the PhD path, often consulting firms will hire you a year in advance of your start date, because they know that you need some time to wrap up your research and defend. Another reason to start preparing and thinking about your path early! 


First: Applications open to PhD and post doc-focused summer programs in the spring each year

Second: Many of these summer or 3-day introduction programs then feed into the yearly recruiting pool, which is most active late summer and early fall


An easy way to open a dialogue with a consulting firm is to reach out to their talent acquisition person or general contact email, let them know that you are interested, and ask to confirm their recruitment timelines for someone with your background. 

Michaela Tolman, PhD